What does fap mean

Familial adenomatous polyposis (FAP) is one of the rare gastrointestinalpoliposis syndromes. … The genetic abnormality seen in FAP is a mutation of the resident APC gene on chromosome 5q. Most FAP patients have a known family history. Patients develop hundreds of adenomatous polyps after püberte.

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Familial adenomatous polyposis (FAP) is one of the rare gastrointestinalpoliposis syndromes. Autosomal dominant is a passing multiple organ disease. It is a disease diagnosed with more than 100 polyps in the colorectal system. It occurs at an early age. If left untreated, its transformation into colon cancer is inevitable. The genetic abnormality seen in FAP is a mutation of the resident APC gene on chromosome 5q. Most FAP patients have a known family history. Patients develop hundreds of adenomatous polyps after püberte. FAP is also observed along with some non-colorectal symptoms. FAP, apart from classical syndrome, is divided into subtypes as a variant of attenüe FAP, Turcot, and Gardner. In some fap cases, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to cause a decline in polyp count and size. The most commonly used drugs for this purpose are sulindac, celecoxib, and exisulind, a sulindacmetabolite. Surgical treatment also determines the age of the patient, the prevalence of rectal polyps, the severity of symptoms, and the localization of a desmoid tumor or detected colorectal cancer. Accordingly, some surgical procedures such as ileorectalanastomosis and mucosectomy may be performed in combination with total proctocolectomy and conventional ileostomy, ilealpouch-anal anastomosis or subtotalcolectomy.

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